Surgical Outcome of Epilepsy Caused by Cortical Dysplasia
نویسندگان
چکیده
منابع مشابه
Surgical treatment of intractable epilepsy associated with focal cortical dysplasia.
Focal cortical dysplasias (FCDs) are congenital malformations of cortical development that are a frequent cause of refractory epilepsy in both children and adults. With advances in structural and functional neuroimaging, these lesions are increasingly being identified as a cause of intractable epilepsy in patients undergoing surgical management for intractable epilepsy. Comprehensive histologic...
متن کاملSurgical Treatment of Intractable Epilepsy Associated with Focal Cortical Dysplasia
Focal cortical dysplasias (FCDs), initially thought to be rare, are a common cause of drugrefractory epilepsy in both children and adults. Successful resection and subsequent characterization of FCDs was first described by Taylor et al. in 1971 from pathological specimens obtained in patients treated for intractable temporal lobe epilepsy (Tassi, et al.,2001; Becker, et al.,2002; Tassi, et al.,...
متن کاملOutcome of epilepsy surgery in focal cortical dysplasia.
OBJECTIVE To describe the outcome of surgery in patients with drug resistant epilepsy and a histopathological diagnosis of focal cortical dysplasia. METHODS AND SUBJECTS Analysis of histories and presurgical and follow up data was carried out in 53 patients with a histological diagnosis of focal cortical dysplasia. Their mean age was 24.0 years (range 5 to 46), and they included 14 children a...
متن کاملFocal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcome.
Since the original description by Taylor, the term focal cortical dysplasia has been used to refer to a wide range of alterations of the cortical mantle. More recently, these conditions have been described from neuroimaging, neuropathological and genetic standpoints, generating several classifications. It is widely recognized that these classifications are unsatisfactory. We propose a simplifie...
متن کاملAltered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy
Focal cortical dysplasia (FCD) is a common cause of pharmacologically-intractable epilepsy, however, the precise mechanisms underlying the epileptogenicity of FCD remains to be determined. Neuropeptide Y (NPY), an endogenous anticonvulsant in the central nervous system, plays an important role in the regulation of neuronal excitability. Increased expression of NPY and its receptors has been ide...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2005
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.0013-9580.2005.461008.x